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The American scientists have opened the mechanism of regeneration of a cardiac muscle which usually works only for an embryo and ceases to operate after a birth. New data can help all patients who have transferred a heart attack of a myocardium. Employees of the Californian university in San Francisco have found out the complex alarm mechanism which forces cages of different types to restore heart. |
“Фибробласты as actively participate in development of many other things of types of fabrics, such as fabrics of a skin, a breast, lungs and even some cancer tumours. Our results can give more extensive sight at development, functioning and illnesses of fabrics”, – the head of research, professor Dipak Strivatsava confirms.
Its command of scientists has learnt to grow up “in one test tube” different types of cages thanks to what it was possible to find out influence фибробластов on development of cages of a cardiac muscle. Experimenters have established, that in development of a human fruit фибробласты actively support reproduction кардиомиоцитов, and at adult people this process practically stops. Thus management of processes of cell fission of a cardiac muscle is carried out through an alarm molecule which has received the name b1 интегрин.
For check of the opening researchers have deduced special breed of mice in which organism there was no this an alarm molecule. As a result at the majority of germs of rodents high-grade heart had not time to be generated, and they perished to birth. Now scientists намерены to make return experiment and to try to give to adults фибробластам properties эмбриональных cages that the human body could restore the damaged fabrics of heart independently.